Human Tissue Therapy

Homologous Use ONLY

HTT utilizes donated, processed human cells and tissues to promote repair and reconstruction. A variety of different cell and tissue types have been used for HTT, including:

  • Amniotic Tissue is used routinely for the treatment of topical wound defects
  • Human Collagen is administered routinely to address skin defects.
  • Donated Cartilage can address various joint conditions in the upper and lower extremities.
  • Tendon Grafts are routinely implanted to address sports injuries.
  • Human Bone Allografts are used for bone fusions in orthopedic indications.

Human Tissue Therapy Characteristics

HTT may involve either structural tissues or cells/nonstructural tissues, depending  on the characteristics of the tissue in the donor. HTTs may only be used in the recipient patient for the same basic function as the cells/tissue functioned in the  donor (homologous use). Some of the functions of different types of tissues are described below:

Tissue Scaffold

Some types of HTT may be used as a structural scaffold that supports the cellular  activity required for reconstruction of the patient’s tissue

Insurance Coverage Might Be Available

Insurance plans may cover certain human tissue therapy.

Talk to your health care provider to find out if your insurance plan qualifies for Human Tissue Therapy reimbursement.

Disclaimer: None of the statements on this page are intended to make any claims about HTT, but instead describe many of the basic functions of native human tissue.  Per FDA Guidance, it is not necessary for the HCT/P in the recipient to perform all of the basic functions it performed in the donor in order to meet the definition of homologous use. Human Tissue Therapy, as we use that term on this website, are minimally manipulated cells and tissues intended for homologous use only. None of the mentioned statements have been evaluated by the FDA. As defined in 21 CFR 1271.3(c), homologous use means the repair, reconstruction, replacement, or supplementation of a recipient’s cells or tissues with an HTT/P that performs the same basic function or functions in the recipient as in the donor. Human Tissue Therapies are not intended to diagnose, treat, cure or prevent any disease including COVID-19.